Yann Gambin Selected Research

SOXF Transcription Factors

11/2021	A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.
1/2019	R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma.
5/2018	Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach.
1/2017	Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

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Yann Gambin Research Topics

Disease

8	Parkinson Disease (Parkinson's Disease) 01/2021 - 04/2009
4	Neoplasms (Cancer) 01/2021 - 05/2018
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 04/2016
2	Infections 05/2022 - 01/2020
2	Telangiectasis (Telangiectasia) 11/2021 - 01/2019
2	Hypotrichosis 11/2021 - 01/2019
2	Lymphedema (Milroy Disease) 11/2021 - 01/2019
2	Disease Progression 01/2021 - 01/2021
1	Synucleinopathies 01/2022
1	COVID-19 12/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2020
1	Bacterial Infections (Bacterial Infection) 03/2019
1	Vascular Neoplasms (Neoplasms, Vascular) 01/2019
1	Hemangioma (Angioma) 01/2019
1	Edema (Dropsy) 01/2019
1	Necrosis 01/2019
1	Vascular Diseases (Vascular Disease) 01/2019
1	Neoplasm Metastasis (Metastasis) 05/2018
1	Inflammation (Inflammations) 01/2018
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Alzheimer Disease (Alzheimer's Disease) 08/2009

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 05/2022 - 10/2012
6	SynucleinsIBA 01/2022 - 10/2012
4	SOXF Transcription FactorsIBA 11/2021 - 01/2017
4	alpha-SynucleinIBA 01/2021 - 04/2009
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2019
3	Intrinsically Disordered ProteinsIBA 01/2018 - 04/2009
2	Amyloid (Amyloid Fibrils)IBA 01/2020 - 12/2019
1	InterferonsIBA 05/2022
1	Peptide Hydrolases (Proteases)FDA Link 12/2021
1	PapainIBA 12/2021
1	PolyproteinsIBA 12/2021
1	Viral ProteasesIBA 12/2021
1	CytokinesIBA 12/2021
1	Death-Associated Protein KinasesIBA 01/2021
1	octyl-beta-D-glucoside (octyl glucoside)IBA 01/2021
1	early endosome antigen 1IBA 01/2021
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2021
1	Golgi Matrix ProteinsIBA 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021
1	Peptides (Polypeptides)IBA 01/2021
1	Phosphates (Orthophosphate)IBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	3,3'-Diaminobenzidine (3,3 Diaminobenzidine)IBA 01/2021
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	CaveolinsIBA 01/2021
1	Green Fluorescent ProteinsIBA 01/2021
1	Caveolin 1IBA 01/2021
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2021
1	Maltose-Binding ProteinsIBA 01/2021
1	Ascorbate PeroxidasesIBA 01/2021
1	PrionsIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2019
1	Adrenergic Antagonists (Antiadrenergic Agents)IBA 01/2019
1	Propranolol (Inderal)FDA LinkGeneric 01/2019
1	trimethyloxamine (trimethylamine N-oxide)IBA 10/2012
1	Urea (Carbamide)FDA LinkGeneric 10/2012
1	Prion ProteinsIBA 01/2010
1	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)IBA 08/2009
1	LipidsIBA 08/2009

Therapy/Procedure

1	Therapeutics 01/2019